In this issue of “Progress in Medicine” dedicated to endocrinology readers will find three original articles, two interesting case reports and seven review articles.

Kasperlik-Załuska in the original article on Addison’s disease, through long-term observation has shown that in some patients it comes to seroconversion of positive to negative result of antiadrenal antibodies. This is an important observation which may explain the absence of anti-adrenal 21-hydroxylase antibodies in the proportion of individuals with this disease.

Misiorowska, basing on her research conducted on the supply of vitamin D in pregnant women in the Warsaw agglomeration stated that the majority of pregnant women do not adhere to the recommendation of Polish Gynecological Society regarding vitamin D supplementation or apply too law dose of this vitamin, which in consequence have various adverse effects on pregnancy. The recommended dose of 1500-2000 IU/d should be ordered by obstetrician at the first control visit.

Majos and Zgliczyński comparing the efficiency of short-acting somatostatin analogues demonstrated the superiority of the new analog pasireotide over the previously used octreotide. So, it can be expected that in the future pharmacotherapy of acromegaly, especially in cases resistant to currently used analogs, such treatment should be more effective with the use of newly developed pasireotide.

Papierska in a review article writes how to treat adrenal insufficiency effectively and safely. In addition she discusses the possible impact of used medication on metabolic and cardiovascular outcomes and informs about new hydrocortisone formulations.