Liver cirrhosis is the end stage of liver damage that can be caused by various factors including but not limited to viral infections, toxic damage and metabolic diseases. The impairment of liver function does not result only in protein synthesis or bilirubin conjugation, but also is related to higher bacterial infection rate (1). This phenomenon can be explained by intestinal bacterial overgrowth and increased bacterial translocation (2, 3). The most common infections are urinary tract infection and spontaneous bacterial peritonitis, followed by pneumonia, soft tissue, skin infections and bacteraemia (3). Another complication related to liver cirrhosis is hepatic encephalopathy. Its pathology is multifactorial; however among the others it includes the metabolism of ammonia. The production of ammonia it higher, if bacterial overgrowth is present (4). The hyperammonemia influences the induction of encephalopathy through promotion of cerebral oedema, modulation of the blood-brain barrier and neuroinhibition (4-6). Importantly bacterial infections seem to be underestimated cause of liver function impairment and hepatic encephalopathy. We describe a case report illustrating an association between liver function, complications of liver cirrhosis and multiple bacterial infections.